Whoppers are tall, fat zombies of exceptional size and strength that appear in Resident Evil 6. It is not clear if their bulk is the result of a mutation or not, though it seems more likely as the C-virus attacks created a greater number of zombies than people in very little time, meaning that there would already be a fleeting number of people for any zombies to consume to gain that kind of weight.

Whoppers use their tremendous bulk to knock down potential prey and stun them, or simply crush them under their great weight. Stunned victims are usually then picked up in the Whopper's chubby arms as it eats them. Its body consists of layers of cold, dead blubber which easily absorb impacts, but it moves very slowly due to its weight and can be stopped permanently by damaging its legs.