Cephalo is a mutation of Las Plagas that appears in Resident Evil 5. In many areas of the game, if a Majini is damaged harshly enough, a mature Plaga will erupt from its neck stump if the head is destroyed. It appears as a centipede-type creature with a long tentacle-shaped head that ends in a jagged blade. The Cephalo will use its bladed head to slash at nearby enemies, so maintaining distance is advised due to the creature's impressive reach. Once the parasite emerges, attacking its host body does little damage and can only be killed quickly by aiming for the parasite itself. Alternatively, the parasite can be killed instantly by exposing it to the fierce ultraviolet light of a flash grenade.